Yes, Ponce de León had several indigenous allies during his explorations and conquests in the Americas. One of his most notable alliances was with the Taíno people of Puerto Rico, who provided him with valuable assistance and support during his early expeditions. The Taínos helped him navigate the island, provided him with food and supplies, and served as guides and interpreters. Ponce de León also formed alliances with other indigenous groups in the region, such as the Caribs and the Guaraní, who helped him in his explorations of Florida and other parts of the Caribbean. These alliances were crucial to Ponce de León's success and enabled him to establish a foothold in the Americas.