- Furs: Fur pelts were a valuable commodity in Europe, where they were used to make clothing, hats, and other goods. The most common furs traded by First Nations were beaver, otter, and mink.
- Sea otter skins: Sea otter pelts were especially prized by European fur traders, as they were considered to be the finest quality fur available. The sea otter trade was a major factor in the European exploration of the Pacific Northwest.
- Medicinal herbs and plants: First Nations had a deep knowledge of the medicinal properties of local plants and herbs. They traded these with Europeans, who were eager to learn about new ways to treat diseases.
- Food: First Nations also traded food with Europeans. This included dried meat, fish, and other provisions that were essential for survival in the harsh North American climate.
- Canoes and other watercraft: First Nations were skilled canoe builders, and they traded canoes and other watercraft with Europeans. These vessels were essential for transportation and trade in the inland waters of North America.
-Slaves: First nations also traded slaves with the europions which would be sent to the Caribbean to work on sugar and tobacco plantations.