- Major General George B. McClellan (November 1, 1861 – November 7, 1862)
- Major General Ambrose Burnside (November 9, 1862 – January 25, 1863)
- Major General Joseph Hooker (January 26, 1863 – June 28, 1863)
- Major General George G. Meade (June 28, 1863 – April 9, 1865)