Her background as an enslaved African greatly influenced her writing about the Middle Passage, the forced transportation of enslaved Africans across the Atlantic. In her poem "On Being Brought from Africa to America," she reflects on the horrors of the Middle Passage and the suffering of her fellow Africans. She writes:
"'Twas mercy brought me from my Pagan land,
Taught my benighted soul to understand
That there's a God, that there's a Saviour too:
Then I repent of all that I have done,
And mourn that I was born to be undone.'"
Wheatley's poem is a powerful indictment of the slave trade and a testament to the resilience of the human spirit. Through her writing, she gave voice to the voiceless and helped to bring about a greater awareness of the inhumanity of slavery.