Although historical accounts and medical knowledge support the existence of ergotism in Europe and surrounding regions, where Salem is located, there is no conclusive evidence directly linking ergot poisoning to specific cases of witchcraft accusations or hysteria during the Salem witch trials. Other factors, such as social, religious, and political tensions, played significant roles in fueling the witch-hunting phenomenon, and blaming the entire episode solely on ergot is an oversimplification.
Moreover, scientific scrutiny of the potential role of ergot in Salem witch-hunting remains limited due to the absence of toxicological analyses or historical records explicitly indicating its involvement. Further research, historical examinations, and interdisciplinary collaboration would be necessary to establish a more substantial connection between ergot and the events of the Salem witch trials.