- John Adams: The second President of the United States was born in Quincy, Massachusetts. He was a leading figure in the American Revolution and served as the nation's first Vice President.
- John Quincy Adams: The sixth President of the United States, son of John Adams, was also born in Quincy, Massachusetts. He served as Secretary of State under President James Monroe and negotiated the Treaty of Ghent, which ended the War of 1812.
- Benjamin Franklin: One of the most famous figures in American history, Benjamin Franklin was born in Boston, Massachusetts. He was a polymath who made significant contributions to science, politics, and literature. He is credited with inventing the lightning rod and the bifocals, and he was a prominent figure in the American Revolution.
- Henry David Thoreau: Thoreau was a transcendentalist philosopher, poet, and naturalist. He is best known for his book "Walden," which recounts his experiences living in a small cabin in the woods for two years.
- Emily Dickinson: Dickinson was a reclusive poet who lived in Amherst, Massachusetts. She wrote over 1,800 poems, most of which were published posthumously. She is considered one of the most important poets in American literature.
- W.E.B. Du Bois: Du Bois was a civil rights activist, sociologist, and historian. He was a co-founder of the National Association for the Advancement of Colored People (NAACP) and wrote several influential works on race relations.
- John Fitzgerald Kennedy: The 35th President of the United States was born in Brookline, Massachusetts. He was a charismatic leader who served as President during the Cuban Missile Crisis and the Civil Rights Movement.
- Robert Frost: Frost was a poet who won four Pulitzer Prizes for Poetry. He is best known for his poems about rural life in New England.
- Malcolm X: Malcolm X was a civil rights activist and a prominent member of the Nation of Islam. He was a powerful orator who spoke out against racial injustice.
- Amelia Earhart: Earhart was a pioneering aviatrix who set many world records for women. She disappeared over the Pacific Ocean while attempting to fly around the world in 1937.