In 750 BCE, Piye, the Nubian king of the Kingdom of Kush, invaded and conquered Egypt, establishing the Twenty-fifth dynasty of Egypt.
In 1347, the plague first entered the Mediterranean through trading ships carrying goods from the Black Sea territories of the Golden Horde. The disease then spread across Europe, the Middle East, and North Africa, claiming up to 60% of the population in a large-scale outbreak known as the Black Dea