- Tupac Amaru II: He led a major rebellion in Peru against Spanish rule in 1780. Tupac Amaru II proclaimed himself as the rightful Inca ruler and aimed to restore the Inca Empire. His rebellion spread throughout the region, but it was ultimately crushed by the Spanish forces.
- Miguel Hidalgo: Hidalgo, a Mexican priest, is considered one of the main figures of the Mexican War of Independence. In 1810, he issued the Grito de Dolores (Cry of Dolores), which called for the end of Spanish rule and the start of the independence movement.
- Simón Bolívar: Bolívar led independence movements in South America against the Spanish Empire. He is regarded as a key figure in the emancipation of several countries, including Venezuela, Colombia, Ecuador, Peru, and Bolivia.
- José de San Martín: Along with Simón Bolívar, José de San Martín played a pivotal role in the South American independence movements. He led the Andes Army across the Andes Mountains to liberate Chile and Peru from Spanish rule.
- Toussaint Louverture: Toussaint Louverture was the leader of the Haitian Revolution, which began in 1791. Louverture and his forces successfully fought against the French and Spanish forces, leading to the independence of Haiti in 1804.
- José Rizal: Rizal was a Filipino nationalist, writer, and physician who advocated for political reforms during the Spanish colonial period in the Philippines. His writings, including the novels Noli Me Tangere and El Filibusterismo, inspired the Philippine Revolution against Spanish rule.
These are just a few examples of the numerous leaders who led revolts and independence movements against Spanish rule in different parts of the Americas.