- Uninhabited - The deserts are vast and sparsely populated, making it easier to contain the immediate effects of the explosions and mitigate the risk of immediate radiation exposure to large number of people.
- Isolation - The remote locations of many desert areas allowed for greater control and security during testing, minimizing the risk of unauthorized access and potential interference.
- Large Open Space - The expansive stretches of desert provided sufficient space to conduct large scale experiments, including airbursts and large yield explosions, while also facilitating the construction of necessary facilities and infrastructure.
- Minimal Infrastructure - The lack of significant human activity in many deserts meant that there was minimal pre-existing infrastructure to be damaged or affected by the test explosions, reducing the potential for collateral damage.
- Geological Suitability - The geological features and the composition of certain deserts, such as the presence of stable soil and rock formations, made them suitable for constructing bunkers and other structures needed to monitor and record the explosions.
- Weather Conditions - The generally dry and stable weather conditions in many deserts provided predictable and favorable atmospheric conditions for conducting tests with minimal interference from adverse weather events, such as storms and heavy rainfall.