The Black Death first struck port cities because these areas were often the first points of contact between people from different regions. When ships arrived from other countries, they often brought rats and fleas carrying the plague. These rats and fleas would then spread to the local population, causing widespread infection and death.
Port cities were also particularly vulnerable to the Black Death because they were often densely populated and had poor sanitation conditions. This made it easier for the disease to spread from person to person. In addition, port cities were often home to large numbers of travellers and merchants, who may have unknowingly carried the disease from one place to another.
The Black Death had a devastating impact on Europe and Asia. It is estimated that the pandemic killed between 30 and 60% of the population of Europe, and it had a similar impact in Asia. The disease caused widespread social and economic disruption, and it led to a number of changes in the way people lived their lives.